The PerfectCLEAN Post
KLORESE
KLORESE: Neutralizing What Traditional Disinfectants Leave Behind
Healthcare facilities do not struggle with a lack of disinfectants. They struggle with a lack of disinfectants that can realistically support the full complexity of healthcare cleaning and disinfection.
Especially when the disinfectants aren’t used properly.
Infection Prevention and Environmental Services teams are asked to manage a growing list of risks across diverse care settings. Patient rooms, restrooms, emergency departments, waiting areas, nursing stations, shared equipment, sinks, drains, and other high-touch surfaces all present different challenges.
Pathogens vary. Soil loads vary. Contact times vary. Safety considerations vary. Staff workflows vary. Yet the expectation remains the same: clean thoroughly, disinfect effectively, reduce risk, and do it all without worrying about patient and staff safety and contributing to antimicrobial resistance.
These are the challenges KLORESE was developed to solve.
KLORESE is designed to answer a fundamental question for healthcare facilities: how can one cleaner and disinfectant support a facility wide , safer, more effective infection prevention strategy?
KLORESE is an EPA registered cleaner and disinfectant that is pH-neutral. KLORESE has broad kill claims, including C. diff spores in 4 minutes, human norovirus, Candida auris, bloodborne pathogens, all ESKAPE pathogens, and biofilm-related applications. It is also the most versatile cleaner/disinfectant with food contact and soft surface, sanitizing claims and is approved for use in electrostatic sprayers.
The Real Problem: Too Many Products, Too Many Gaps
For Infection Prevention and EVS managers, the challenge is rarely just whether a disinfectant can kill a pathogen under lab conditions. The more pressing question is whether that chemistry can help close operational gaps in the real world.
Many facilities still rely on a patchwork approach. One product for routine disinfection. Another for C diff outbreaks. Another for bloodborne pathogens. Another for drains. Another for odor. That product sprawl creates room for confusion, misapplication, training burdens, and inconsistent outcomes.
At the same time, common chemistries such as quaternary ammonium compounds, often referred to as QUAT sanitizer or QUAT disinfectant, may introduce their own limitations.
View QUATs vs. HOCL Chart
QUATs can leave persistent residue, bind to surfaces, cotton mops and wipers, soils, support biofilm formation, and cause respiratory, dermatological, hormonal imbalances,
and environmental concerns. Hypochlorous acid is non-persistent, broad spectrum, more environmentally benign, creates less residue, and is “effectively human.”
This comparison matters in healthcare.
Residue is not a cosmetic issue. Residue interferes with surfaces, contributes to chemical buildup, and complicates cleaning outcomes. Narrower product efficacy can also leave important gaps, especially when facilities are facing hard-to-kill pathogens, spore-formers, or challenging environmental reservoirs.
Why HOCl Changes the Conversation
KLORESE is built on hypochlorous acid chemistry (HOCL). From a safety and efficacy standpoint, that matters. HOCl is the same active antimicrobial molecule produced by the human immune system to fight infections. Or, as we like to say, KLORESE is “effectively human.”
For healthcare operators, the practical implication is straightforward. A pH-neutral HOCl disinfectant can support a wider range of use environments without forcing teams to choose between efficacy and usability. That is especially important in areas where frequent disinfection is required, surfaces vary, and staff need a product that can fit into routine workflows rather than complicate them.
This is where KLORESE becomes more than a chemistry discussion and turns into a protocol discussion. In acute care hospitals, EVS and IP teams need a disinfectant strategy that can move across patient rooms, bathrooms, waiting areas, equipment touchpoints, sinks, and other environmental surfaces with as little friction as possible. The fewer handoffs between products, dilution systems, and exceptions, the easier it is to build repeatable, auditable processes.
C. diff is the Test Many Products Fail
Any serious healthcare disinfection conversation has to address C. diff.
The CDC advises facilities treating confirmed C. diff infection to clean room surfaces daily with an EPA-approved spore-killing disinfectant and to continue those practices during treatment and at discharge or transfer. Contact time and label adherence matter because spores require specific disinfection claims and use directions.
KLORESE has an EPA List K claim for Clostridioides difficile spores and a 4-minute sporicidal contact time.
That distinction is important. A strong infection prevention strategy does not depend on marketing shorthand. It depends on matching the chemistry, the soil conditions, the contact time, and the label claim to the actual risk.
KLORESE gives healthcare teams access to a disinfectant that can fit routine workflows while still covering serious escalation scenarios like C. diff when used correctly.
The Hidden Problem: Biofilm and Water-Associated Reservoirs
Many environmental disinfection discussions stop at visible surfaces. Healthcare risk does not.
One of the strongest points in favor of KLORESE is its role in addressing biofilm-associated contamination. EPA guidance for biofilm claims exists because biofilm presents a different problem than planktonic surface contamination. Bacteria protected inside biofilm are harder to reach and harder to inactivate.
We were once approached by a hospital that faced persistent Stenotrophomonas maltophilia infections in trauma and ICU areas for more than two years. A CDC-supported investigation identified sink drain biofilms as the primary reservoir.
In response, KLORESE was paired with the QUICKfoam-5 system to generate high-density foam that filled drain pipes, evacuated the P-trap in under five minutes, and maximized contact with biofilm-laden surfaces. Follow-up environmental cultures reportedly showed elimination of Stenotrophomonas and other opportunistic pathogens.
Beyond Pathogens: Surface Safety in High-Risk Environments
KLORESE also enters another important conversation: surface safety beyond traditional pathogen control.
PerfectCLEAN’s overview materials state that KLORESE neutralizes 90.8% of fentanyl and 98.5% of methamphetamine in four minutes or less, and note relevance to cytotoxins and other hazardous residues.
In practical terms, that expands the discussion from standard patient care disinfection into higher-risk specialty applications, including areas where healthcare overlaps with emergency response, behavioral health, or partnerships with crime scene cleanup agencies.
Bloodborne pathogens, hazardous drug residue, bodily fluids, and drug contamination may all intersect with environmental cleaning protocols. EPA List S now covers disinfectants with claims against HIV, Hepatitis B, and Hepatitis C, and EPA emphasizes careful label review and contact time compliance for those pathogens as well.
A Simpler Way to Build a Smarter Program
The problem KLORESE solves is not just microbial. It is operational.
Healthcare facilities need disinfectants that align strong efficacy claims with practical deployment. They need chemistries that help reduce product sprawl, support broader protocol standardization, minimize residue concerns, and extend from routine room turnover to harder problems like C. diff, biofilm, bloodborne pathogen response, and hazardous surface contamination.
KLORESE is positioned to help fill that role. Its combination of pH-neutral HOCl chemistry, broad EPA listing support, C. diff efficacy, biofilm relevance, and hazardous residue neutralization makes it a strategic product for facilities that want to strengthen infection prevention without adding unnecessary complexity.
For healthcare leaders evaluating the next step in their environmental hygiene strategy, the question is not whether another disinfectant exists. The question is whether your current disinfectant program is truly built for the realities your teams face every day.
